| Pre-operative staging with positron emission tomography in patients with pelvic recurrence of rectal cancer. | |
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MedLine Citation:
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PMID: 18577865 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIM: The treatment of pelvic recurrences of rectal cancer is primarily surgical. The substantial morbidity and mortality of such resections warrant stringent patient selection. Recent literature reports PET to be of additional value to CT for the detection of metastases in colorectal cancer patients. We studied the clinical impact of PET in pelvic rectal cancer recurrence. METHODS: PET findings in 37 pelvic recurrences of rectal cancer were evaluated retrospectively. Comparison was made to CT and MRI findings. It was analyzed whether PET had been decisive in clinical decision making or could have been so. RESULTS: Thirty-two patients had 37 rectal cancer recurrences. PET differed from conventional imaging in 13 cases (35%): seven PET scans showed lesions that were not seen with CT or MRI. PET scans were negative in six lesions detected by CT or MRI. PET alone changed management in five recurrences (14%). Four PET scans were false-positive; this had clinical implications in 2 patients. CONCLUSION: In a selected population with pelvic rectal cancer recurrences, PET had additional value to conventional imaging, mainly in detecting lymph node metastases. PET findings thus had a significant impact on selection of patients for curative surgery. |
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Authors:
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Ian F Faneyte; Raphaëla C Dresen; Michela A L Edelbroek; Grard A P Nieuwenhuijzen; Harm J T Rutten |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article Date: 2008-06-23 |
Journal Detail:
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Title: Digestive surgery Volume: 25 ISSN: 1421-9883 ISO Abbreviation: Dig Surg Publication Date: 2008 |
Date Detail:
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Created Date: 2008-08-07 Completed Date: 2008-12-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501808 Medline TA: Dig Surg Country: Switzerland |
Other Details:
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Languages: eng Pagination: 202-7 Citation Subset: IM |
Copyright Information:
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(c) 2008 S. Karger AG, Basel. |
Affiliation:
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Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands. ianfaneyte@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology,
radiography,
radionuclide imaging* Adult Aged Female Humans Magnetic Resonance Imaging Male Middle Aged Neoplasm Recurrence, Local / pathology, radiography, radionuclide imaging* Neoplasm Staging / methods Pelvic Neoplasms / radiography, radionuclide imaging*, secondary Positron-Emission Tomography* Preoperative Care / methods Rectal Neoplasms / pathology, radiography, radionuclide imaging* Retrospective Studies Sensitivity and Specificity Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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