| Pre-operative identification of patients at high risk of deep venous thrombosis after elective major abdominal surgery. | |
| | |
MedLine Citation:
|
PMID: 2871419 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Eighteen items of clinical and laboratory information were measured on the day before operation in 85 patients who underwent elective major abdominal surgery. Postoperatively, deep venous thrombosis (DVT) was detected by 125I-fibrinogen scan in 23 patients. Stepwise logistic discriminant analysis was used to identify factors which predicted DVT. Seven such factors were identified, which were then used to construct a predictive index. In descending order of predictive power, they were: age, euglobulin lysis time (ELT), previous abdominal surgery, varicose veins, antithrombin III concentration, cigarette smoking, and platelet count. Pre-operatively, the predictive index correctly identified 91% of the patients in whom DVT developed, and wrongly allocated to the high-risk group 19% of those in whom it did not. A shortened version of the predictive index based only on age and ELT (I = -11.5 + 0.133 age + 0.006 ELT) was 91% sensitive and 63% specific in the prediction of DVT. In a prospective study of 43 patients, this shortened predictive index correctly identified pre-operatively 93% of patients in whom DVT developed, and wrongly allocated to the high-risk group only 17% of those in whom it did not. |
| | |
Authors:
|
H M Sue-Ling; D Johnston; M J McMahon; P R Philips; J A Davies |
Related Documents
:
|
7257029 - The effects of low-dose heparin treatment on patients undergoing transvesical prostatec... 12772129 - Mechanical thrombectomy for the treatment of lower extremity deep vein thrombosis. 19419779 - Treatment failure of low molecular weight heparin bridging therapy before a cardiac sur... 20926329 - Patient tolerance of neuromuscular electrical stimulation (nmes) in the presence of ort... 18241919 - Prospective evaluation of coagulopathy in multiple myeloma patients before, during and ... 2193559 - D-dimer and thrombin-antithrombin iii complex levels uncorrelated with phlebographic fi... 12381639 - Surgical closure of atrial septal defects in adults: effect of age at operation on outc... 9234129 - Long-term results with the palmaz stent in the superficial femoral artery. 20981209 - Risk factors for treatment failure and recurrence after metronidazole treatment for clo... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Lancet Volume: 1 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1986 May |
Date Detail:
|
Created Date: 1986-06-23 Completed Date: 1986-06-23 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 1173-6 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abdomen
/
surgery* Adult Age Factors Aged False Positive Reactions Female Fibrinogen / diagnostic use Humans Iodine Radioisotopes / diagnostic use Male Middle Aged Obesity / complications Postoperative Complications / diagnosis* Preoperative Care Prognosis Prospective Studies Risk Serum Globulins / analysis Thrombophlebitis / diagnosis* Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Iodine Radioisotopes; 0/Serum Globulins; 9001-32-5/Fibrinogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of vitamin A supplementation on childhood mortality. A randomised controlled community trial.
Next Document: Lipoprotein abnormalities in insulin-dependent diabetes mellitus.