Document Detail


Pre-operative evaluation of peritoneal deposits using multidetector computed tomography in ovarian cancer.
MedLine Citation:
PMID:  20858663     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In the management of epithelial ovarian cancer (EOC), the identification of peritoneal deposits is the most important prognostic factor. We conducted a prospective study to evaluate the role of multidetector CT (MDCT) in identifying peritoneal deposits pre-operatively.
METHODS: 38 previously untreated patients (median age 50 years; range 26-70 years) were evaluated with contrast-enhanced MDCT of the abdomen and pelvis. All CT scans were performed on a four-slice MDCT scanner with thin-slice image acquisition. Multiplanar coronal, sagittal or oblique images were constructed and all images were reviewed by at least two radiologists. The extent of disease was determined and mapped for all areas of the abdomen and pelvis. CT scans were reviewed and compared with surgical findings. Peritoneal deposits and thickening were separately noted for each of the nine segments of the abdomen and pelvis (i.e. bilateral hypochondria, bilateral lumbar, bilateral iliac fossa, epigastrium, umbilical region and hypogastrium) and were mainly used to determine the accuracy of MDCT in the depiction of peritoneal carcinomatosis.
RESULTS: Sensitivity, specificity, positive and negative predictive values and accuracy of CT in the detection of peritoneal deposits were similar to those reported in the literature. The most common anatomical sites to have peritoneal deposits were the pouch of Douglas (18 cases) and the right subdiaphragmatic region (18 cases).
CONCLUSION: Despite the improved scanning technology, image reconstruction and viewing ability of MDCT, its overall accuracy for the detection of peritoneal deposits is not significantly improved when compared with conventional CT; however, MDCT is useful in the assessment of disease at specific locations in the abdomen and pelvis.
Authors:
S H Chandrashekhara; S Thulkar; D N Srivastava; L Kumar; R Hariprasad; S Kumar; M C Sharma
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Publication Detail:
Type:  Journal Article     Date:  2010-09-21
Journal Detail:
Title:  The British journal of radiology     Volume:  84     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-21     Completed Date:  2011-02-09     Revised Date:  2011-08-29    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  38-43     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India. drchandruaiims@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Humans
Middle Aged
Neoplasm Staging
Ovarian Neoplasms / pathology,  radiography*
Peritoneal Neoplasms / radiography*,  secondary*
Peritoneum / pathology,  radiography*
Preoperative Care / methods
Prognosis
Prospective Studies
Tomography, X-Ray Computed / methods*
Comments/Corrections
Comment In:
Br J Radiol. 2011 Aug;84(1004):768   [PMID:  21750141 ]

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