Document Detail


Pre-metrological (pre-analytical) variation of some biochemical quantities.
MedLine Citation:
PMID:  10616754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It is customary to assume that pre-metrological variation is negligible if all pre-metrological sources of variation have been standardised. The aim of this study was to quantify the pre-metrological variation of some biochemical quantities frequently measured in clinical laboratories. The experimental design considers the different sources of pre-metrological variation that usually act day-to-day on samples from patients. The results demonstrate that, for many quantities, the pre-metrological variance is not negligible; consequently, it is suggested that these variances should be taken into account when estimating the uncertainty of measurement of patients' results.
Authors:
X Fuentes-Arderiu; G Acebes-Frieyro; L Gavaso-Navarro; M J Castiñeiras-Lacambra
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical chemistry and laboratory medicine : CCLM / FESCC     Volume:  37     ISSN:  1434-6621     ISO Abbreviation:  Clin. Chem. Lab. Med.     Publication Date:  1999 Oct 
Date Detail:
Created Date:  2000-01-13     Completed Date:  2000-01-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9806306     Medline TA:  Clin Chem Lab Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  987-9     Citation Subset:  IM    
Affiliation:
Servei de Bioquímica Clínica, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Llobregat, Catalonia, Spain. xfa@csub.scs.es
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MeSH Terms
Descriptor/Qualifier:
Clinical Chemistry Tests*
Humans
Reproducibility of Results*
Comments/Corrections
Comment In:
Clin Chem Lab Med. 2000 Mar;38(3):263   [PMID:  10905765 ]

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