| Pre-hospital fibrinolysis followed by angioplasty or primary angioplasty in acute myocardial infarction: the long-term clinical outcome. | |
| | |
MedLine Citation:
|
PMID: 14739627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Randomized trials comparing primary angioplasty and in-hospital fibrinolysis in acute myocardial infarction (AMI) have shown an advantage for primary angioplasty. The long-term follow-up of pre-hospital fibrinolysis followed by elective or rescue coronary angioplasty versus primary angioplasty is not well established after acute myocardial infarction. This study sought to assess the long-term clinical outcome of patients with AMI having either received pre-hospital fibrinolysis optimized by coronary angioplasty or primary angioplasty. METHODS: We conducted a retrospective analysis involving 318 patients who either underwent primary angioplasty ( n = 157) or received pre-hospital fibrinolysis followed by an angioplasty (rescue or elective) ( n = 161) within 6 hours of the onset of chest pain. RESULTS: The groups were similar regarding their baseline characteristics except for the ages. No difference was noted for in-hospital mortality (primary PTCA group: 2.48%, combined group: 2.54%; p = ns) with no increased risk of hemorrhage. The 3-year mortality was not significantly different in the two groups (9.7% vs. 4.9%; p = 0.15). Regarding major adverse cardiac events (29.5% vs. 37.5%; p = 0.23), reintervention (22.5% vs. 23.2%; p = 0.99) or target lesion revascularization (16.1% vs. 14.7%; p = 0.68), the groups were statistically similar. CONCLUSION: These data from real-life practice emphasize the safety and similar benefits on the long-term clinical outcome of AMI patients having undergone either pre-hospital fibrinolysis followed by angioplasty or primary angioplasty. |
| | |
Authors:
|
J Roncalli; F Brunelle; M Galinier; D Carrié; J Fourcade; M Elbaz; J P Gaston; S Charpentier; J Puel; J M Fauvel |
Related Documents
:
|
10150917 - Outcome following coronary balloon angioplasty in young adults aged 35 years or less. 10785717 - Coronary angioplasty in the treatment of post-cardiac transplant coronary artery disease. 7987907 - The impact of balloon material and lesion characteristics on the incidence of angiograp... 1499067 - Aortic dissection as complication of percutaneous transluminal coronary angioplasty. 15073977 - A study to determine the sensitivity and specificity of hospital discharge diagnosis da... 8198257 - The effects of intravenous clonidine on regional myocardial function in a canine model ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of thrombosis and thrombolysis Volume: 15 ISSN: 0929-5305 ISO Abbreviation: J. Thromb. Thrombolysis Publication Date: 2003 Jun |
Date Detail:
|
Created Date: 2004-01-23 Completed Date: 2004-10-08 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 9502018 Medline TA: J Thromb Thrombolysis Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 181-8 Citation Subset: IM |
Affiliation:
|
Cardiology Department, CHU Rangueil, 1 avenue Jean Poulhès, 31403 Toulouse Cedex, France. roncalli.j@chu-toulouse.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angioplasty, Transluminal, Percutaneous Coronary* Emergency Medical Services* Female Hospital Mortality Humans Longitudinal Studies Male Middle Aged Myocardial Infarction / complications, mortality, therapy* Retrospective Studies Survival Analysis Thrombolytic Therapy* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Efficacy and safety of a new streptokinase regimen with enoxaparin in acute myocardial infarction.
Next Document: Distance from the coronary ostium to the culprit lesion in acute ST-elevation myocardial infarction ...