Document Detail


Pre-exercise carbohydrate status influences carbohydrate-mediated attenuation of post-exercise cytokine responses.
MedLine Citation:
PMID:  18615388     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Most studies investigating the effects of acute carbohydrate (CHO) ingestion on post-exercise cytokine responses have involved fasted athletes. This study characterised the effects of acute CHO beverage ingestion preceded by consumption of a CHO-containing pre-exercise meal. Sixteen highly-trained male cyclists/triathletes (age: 30.6 +/- 5.6 y; V O (2max): 64.8 +/- 4.7 ml . kg . min (-1) [mean +/- SD]) undertook two cycle ergometry trials involving randomised consumption of a 10 % CHO beverage (15 mL . kg (-1) . hr (-1)) or water (H (2)O). Trials were undertaken 2 h after a breakfast providing 2.1 g CHO . kg (-1) body mass (BM) (48 kJ . kg (-1) BM) and consisted of 100 min steady state cycle ergometry at 70 % V O (2max) followed by a time trial of approximately 30 min duration. Blood samples were collected pre-, post- and 1 h post-exercise for measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance was not substantially different between CHO and H (2)O trials (4.5 %, p = 0.42). Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to the H (2)O trial. There was a substantial reduction in IL-10 (32 %, p = 0.05) and IL-1ra (43 %, p = 0.02) responses at 1 h post-exercise with CHO compared to H (2)O ingestion. In conclusion, the previously shown attenuating effects of CHO ingestion during exercise on cytokine responses appear reduced when athletes consume a CHO-containing pre-exercise meal.
Authors:
A J Cox; D B Pyne; G R Cox; R Callister; M Gleeson
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2008-07-09
Journal Detail:
Title:  International journal of sports medicine     Volume:  29     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-10-31     Completed Date:  2009-03-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1003-9     Citation Subset:  IM    
Affiliation:
Department of Physiology, Australian Institute of Sport, Belconnen, Australia. amanda.cox@newcastle.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adult
Bicycling / physiology*
Blood Glucose
Cytokines*
Dietary Carbohydrates / metabolism*
Energy Metabolism*
Ergometry / instrumentation
Exercise / physiology*
Exercise Test
Humans
Male
Nutritional Status*
Oxygen Consumption
Time Factors
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Cytokines; 0/Dietary Carbohydrates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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