Document Detail

Pre-eclampsia and thrombophilia.
MedLine Citation:
PMID:  12787537     Owner:  NLM     Status:  MEDLINE    
Pre-eclampsia is a major cause of perinatal and maternal morbidity and mortality worldwide. Although knowledge of the precise aetiology remains uncertain a number of risk factors have been described. Thrombophilias have been associated with pre-eclampsia in a number of studies and it is biologically plausible that they may contribute to the uteroplacental thrombosis that is frequently seen in pre-eclampsia. If this association is confirmed, there is the potential to investigate preventive treatments, including low-molecular-weight heparins, aspirin and folate.
Joanne Said; Gustaaf Dekker
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical obstetrics & gynaecology     Volume:  17     ISSN:  1521-6934     ISO Abbreviation:  Best Pract Res Clin Obstet Gynaecol     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-05     Completed Date:  2003-08-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  101121582     Medline TA:  Best Pract Res Clin Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  441-58     Citation Subset:  IM    
Department of Perinatal Medicine, The Royal Women's Hospital, Melbourne, Australia.
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MeSH Terms
Blood Coagulation
Pre-Eclampsia / etiology*,  prevention & control
Pregnancy Complications, Hematologic*
Risk Factors
Thrombophilia / complications*

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