| Pre-eclampsia: pathophysiology, diagnosis, and management. | |
| | |
MedLine Citation:
|
PMID: 21822394 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
The incidence of pre-eclampsia ranges from 3% to 7% for nulliparas and 1% to 3% for multiparas. Pre-eclampsia is a major cause of maternal mortality and morbidity, preterm birth, perinatal death, and intrauterine growth restriction. Unfortunately, the pathophysiology of this multisystem disorder, characterized by abnormal vascular response to placentation, is still unclear. Despite great polymorphism of the disease, the criteria for pre-eclampsia have not changed over the past decade (systolic blood pressure >140 mmHg or diastolic blood pressure ≥90 mmHg and 24-hour proteinuria ≥0.3 g). Clinical features and laboratory abnormalities define and determine the severity of pre-eclampsia. Delivery is the only curative treatment for pre-eclampsia. Multidisciplinary management, involving an obstetrician, anesthetist, and pediatrician, is carried out with consideration of the maternal risks due to continued pregnancy and the fetal risks associated with induced preterm delivery. Screening women at high risk and preventing recurrences are key issues in the management of pre-eclampsia. |
| | |
Authors:
|
Jennifer Uzan; Marie Carbonnel; Olivier Piconne; Roland Asmar; Jean-Marc Ayoubi |
Related Documents
:
|
14587894 - Water quality guidance for protection of freshwater mussels (unionidae) from ammonia ex... 9346604 - Parenthood after liver transplantation. 7553874 - Generation of committed erythroid bfu-e and cfu-e progenitors does not require erythrop... 7457104 - Spontaneous rupture of the liver in pregnancy. 9849704 - Thromboxane and prostacyclin in maternal and fetal circulation in pre-eclampsia. 2565254 - The stability and short-term fluctuation in serum oxytocinase activity in pregnancy. |
Publication Detail:
|
Type: Journal Article Date: 2011-07-19 |
Journal Detail:
|
Title: Vascular health and risk management Volume: 7 ISSN: 1178-2048 ISO Abbreviation: Vasc Health Risk Manag Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-08-08 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101273479 Medline TA: Vasc Health Risk Manag Country: New Zealand |
Other Details:
|
Languages: eng Pagination: 467-74 Citation Subset: IM |
Affiliation:
|
Department of Gynecology and Obstetrics, Hôpital Foch, Suresnes, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Therapeutic potential of rivaroxaban in the prevention of venous thromboembolism following hip and k...
Next Document: Increased reactive oxygen metabolites is associated with cardiovascular risk factors and vascular en...