Document Detail

Pre-eclampsia: Fetal assessment and neonatal outcomes.
MedLine Citation:
PMID:  21474384     Owner:  NLM     Status:  Publisher    
Pre-eclampsia is associated with a number of short- and long-term perinatal and neonatal complications, including death. These are mostly related to birth weight and gestational age at delivery, and therefore are most relevant to severe or early onset pre-eclamptic toxaemia. Currently, little information is available on the optimal antenatal testing modality to be used for pre-eclampsia. Significant limitations are associated with fetal movement counts and the biophysical profile. Evidence is accumulating, however, to support the incorporation of umbilical artery and venous Doppler velocimetry in the evaluation of such fetuses, especially in cases of associated placental insufficiency. Pre-eclampsia might confer some survival advantage to small gestational age infants and prematurely born infants compared with infants born after spontaneous preterm labour. The degree of intrauterine growth restriction also has a negative effect on early morbidity. Longer term outcomes for prematurely born infants are dependent on gestational age, and it is unclear whether the survival advantage conferred by pre-eclampsia translates into better long-term neurodevelopmental outcomes. Abnormal umbilical artery flows might predict poorer cognitive outcomes, although evidence for this is not strong.
Andrée Gruslin; Brigitte Lemyre
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-5
Journal Detail:
Title:  Best practice & research. Clinical obstetrics & gynaecology     Volume:  -     ISSN:  1532-1932     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121582     Medline TA:  Best Pract Res Clin Obstet Gynaecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynaecology and Newborn Care, The Ottawa Hospital, University of Ottawa, 501 Smyth Road, Suite 8425, Ottawa, Ontario K1H 8L6, Canada.
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