Document Detail


Pre-acclimatization to high altitude using exercise with normobaric hypoxic gas mixtures.
MedLine Citation:
PMID:  1483779     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pre-acclimatization was conducted using a new method elaborated in our laboratory, combining high intensity exercise while breathing hypoxia normobaric gas mixtures. The training consisted in a daily training during three weeks, 6 days a week, two hours a day, on bicycle ergometer. Eighteen subjects aging 22.2 +/- 1.4 years (11 males, 7 females) were matched in two similar groups: one group trained in normoxic conditions (NG) while the other group (HG) trained with a progressive decrease of the fraction of inspired oxygen (from 12.2% to 10.0%). Maximal oxygen uptake (VO2max) were measured before and after the protocol period in both hypoxic (VO2max H, FIO2 = 10.4%) and normoxic (VO2max N) conditions, for the 2 groups. Training induced a similar O2max N increase in the two groups. The ratio VO2max H/VO2max N was calculated. As expected, in NG group, this ratio decreased significantly (from 63.9 +/- 4.3 to 57.5 +/- 3.1%, p < 0.01) after the training period compared to the initial value, diminution associated with an elevation of VO2max N (from 48.4 +/- 9.0 to 52.9 +/- 9.0 ml.min-1 x kg-1, p < 0.01). Conversely, in HG group, this ratio was not significantly diminished (from 61.7 +/- 3.8 to 60.5 +/- 5.2%, NS) in spite of a similar increase of VO2max N (from 47.5 +/- 5.5 to 50.7 +/- 4.9 ml.min-1 x kg-1, p < 0.01). This does not follow the diminution of the ratio usually described when VO2max N reach higher values.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
H Benoit; M Germain; J C Barthélémy; C Denis; J Castells; D Dormois; J R Lacour; A Geyssant
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of sports medicine     Volume:  13 Suppl 1     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1993-02-18     Completed Date:  1993-02-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  S213-6     Citation Subset:  IM; S    
Affiliation:
Laboratoire de Physiologie-GIP Exercise, Faculté de Médecine, Université Jean Monnet, Saint-Etienne, France.
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MeSH Terms
Descriptor/Qualifier:
Acclimatization / physiology*
Adaptation, Physiological / physiology
Adult
Altitude*
Anoxia / physiopathology
Exercise / physiology*
Female
Humans
Male
Nitrogen / administration & dosage*
Oxygen / administration & dosage*
Oxygen Consumption / physiology
Physical Education and Training / methods*
Respiration / physiology
Chemical
Reg. No./Substance:
37291-87-5/nitrox; 7727-37-9/Nitrogen; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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