Document Detail


Praxis induction. Definition, relation to epilepsy syndromes, nosological and prognostic significance. A focused review.
MedLine Citation:
PMID:  24512781     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: There is increasing awareness that reflex epileptic mechanisms provide unique insight into ictogenesis in human epilepsies. Several of the described triggers have in common that they imply complex visuomotor coordination and decision-making; they are today regarded as variations of one principle, i.e. praxis induction (PI). This focused review considers PI from the aspects of history and delineation, clinical and electroencephalographic presentation, syndromatic relations, prevalence, mechanisms of ictogenesis and nosological implications, treatment and prognosis.
METHODS: We reviewed a series of published articles and case reports on PI in order to clarify clinical and electroencephalographic findings, treatment and outcome.
RESULTS: Findings of both induction and inhibition by the same stimuli suggest widening the reflex epilepsy concept into a broader one of epilepsies with exogenous modification of ictogenesis. PI is closely related to juvenile myoclonic epilepsy (JME) where hyperexcitability and hyperconnectivity of the entire network of visuomotor coordination seem to provide the precondition for eliciting reflex myocloni in the musculature active in the precipitating task.
CONCLUSION: The conclusions on ictogenesis derived from PI support the concept of JME as a system disorder of the brain.
Authors:
Elza Márcia Yacubian; Peter Wolf
Publication Detail:
Type:  REVIEW     Date:  2014-1-23
Journal Detail:
Title:  Seizure : the journal of the British Epilepsy Association     Volume:  -     ISSN:  1532-2688     ISO Abbreviation:  Seizure     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-2-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306979     Medline TA:  Seizure     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical heterogeneity of juvenile myoclonic epilepsy: Follow-up after an interval of more than 20 y...
Next Document:  The effects of physical exercise and smoking habits on the expression of SPLUNC1 in nasal lavage flu...