| Pramipexole reduces the prevalence of fatigue in patients with Parkinson's disease. | |
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MedLine Citation:
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PMID: 21963735 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective The aim of this multicenter cross-sectional study was to assess the relation between fatigue in a large number of Japanese patients with Parkinson's disease (PD) and drugs taken to treat PD. Method We used the 16-item Parkinson Fatigue Scale (PFS-16), which was designed to assess fatigue exclusively associated with PD. Multiple logistic regression analyses were used to assess the relation between antiparkinson drugs and fatigue in PD. Results A total of 350 non-demented PD patients were enrolled. Fatigue (PFS score of ≥4) was revealed in 319 patients (91%). Pramipexole was administered to 24% of PD patients. Multiple logistic regression analysis revealed that the administration of Pramipexole was significantly related to low rates of fatigue in PD patients with Hoehn and Yahr stage <3 (p=0.011, odds ratio=5.23, 95% confidence interval; 1.47-18.63). Conclusion The reduced fatigue in PD patients was observed in taking Pramipexole. |
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Authors:
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Akihiko Morita; Yasuyuki Okuma; Satoshi Kamei; Fumihito Yoshii; Toshimasa Yamamoto; Shiori Hashimoto; Hiroya Utsumi; Taku Hatano; Nobutaka Hattori; Miyuki Matsumura; Kazushi Takahashi; Shigeru Nogawa; Yuka Watanabe; Tomoyuki Miyamoto; Masayuki Miyamoto; Koichi Hirata |
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Publication Detail:
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Type: Journal Article Date: 2011-10-01 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 50 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-10-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 2163-8 Citation Subset: IM |
Affiliation:
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Division of Neurology, Department of Medicine, Nihon University School of Medicine, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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