| Pralidoxime in the treatment of carbamate intoxication. | |
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MedLine Citation:
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PMID: 2403479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The use of oxime reactivators of inhibited cholinesterase enzymes in poisoning by carbamate compounds has received mixed reviews in the medical literature. Data are limited and inconsistent on the possible role oxime reactivators might have in carbamate intoxication. Based on existing experience, atropine remains the treatment of choice and pralidoxime (2-PAM) is not recommended except in cases where atropine has first been proven inadequate, in serious mixed poisonings with both carbamate and organophosphorus compounds, or in serious poisonings by unidentified cholinesterase inhibitors. |
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Authors:
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P H Kurtz |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The American journal of emergency medicine Volume: 8 ISSN: 0735-6757 ISO Abbreviation: Am J Emerg Med Publication Date: 1990 Jan |
Date Detail:
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Created Date: 1990-02-07 Completed Date: 1990-02-07 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8309942 Medline TA: Am J Emerg Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 68-70 Citation Subset: IM |
Affiliation:
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California Department of Food and Agriculture, Worker Health and Safety Branch, Sacramento 94271-0001. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Atropine
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therapeutic use Carbamates / poisoning* Cholinesterase Inhibitors / poisoning Drug Interactions Humans Insecticides / poisoning Pralidoxime Compounds / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Carbamates; 0/Cholinesterase Inhibitors; 0/Insecticides; 0/Pralidoxime Compounds; 51-55-8/Atropine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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