| A Pragmatic Contouring Guideline for Salivary Gland Structures in Head and Neck Radiation Oncology: The MOIST Target. | |
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MedLine Citation:
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PMID: 22237147 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES:: One of the main normal tissue toxicities in head and neck radiation oncology is xerostomia. In several studies, reduced radiation dose to the salivary glands has been shown to diminish the effects of gland dysfunction. However, no clear guidelines exist to define the anatomic location of the involved glands on cross-sectional imaging in a pragmatic manner. This study presents an anatomic, computed tomography (CT)-based definition of the major and minor salivary glands. METHODS:: On the basis of information from normal structure anatomy, the location of major and minor salivary glands was identified and translated into a cross-sectional CT-based description of the salivary glands. RESULTS:: The major salivary glands include the parotids and submandibular glands. The minor salivary glands are presented as a part of a surrogate structure (the Minor Oral Including Sublingual Salivary Tissue target), including the minor glands located in the oral mucosa of the tongue, hard and soft palate, buccal mucosa, and inner surface of the lips. CONCLUSIONS:: Clinical implementation of CT-based delineations of the salivary glands according to the proposed guideline should reduce interobserver variability. This may lead to an improved understanding of the relationship between radiation dose and volume and effects on salivary function. |
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Authors:
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Frank Hoebers; Eugene Yu; Avi Eisbruch; Wade Thorstad; Brian O'Sullivan; Laura A Dawson; Andrew Hope |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-10 |
Journal Detail:
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Title: American journal of clinical oncology Volume: - ISSN: 1537-453X ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8207754 Medline TA: Am J Clin Oncol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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*Radiation Medicine Program, Princess Margaret Hospital, University Health Network †Department of Radiation Oncology, University of Toronto ‡Department of Medical Imaging, Princess Margaret Hospital, University Health Network §Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada ∥Department of Radiation Oncology, University of Michigan, Ann Arbor, MI ¶Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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