Document Detail


Practices for prevention, diagnosis and management of postpartum haemorrhage: impact of a regional multifaceted intervention.
MedLine Citation:
PMID:  19538416     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the effectiveness of a multifaceted intervention on practices for prevention, diagnosis and management of postpartum haemorrhage (PPH) and on the prevalence of major PPH in a French perinatal network. DESIGN: Quasi-experimental before-and-after survey. SETTING: All maternity units (n = 19) of a French administrative region, operating as a perinatal network. SAMPLE: One representative sample of all women delivering in the network, one representative sample of women with PPH deliveries and an exhaustive sample of women with major PPH. METHODS: The multifaceted intervention took place between February 2003 and March 2004. Information was retrospectively collected for two periods, 2002 (before the intervention) and 2005 (after). MAIN OUTCOME MEASURES: Practices for prevention, diagnosis and management of PPH and prevalence of major PPH. RESULTS: After the intervention, the pharmacological prevention of PPH increased from 58.8% to 75.9% of vaginal deliveries (P < 10(-4)), and the use of blood collecting bags from 3.9% to 76.3% (P < 10(-4)), but initial PPH management did not change significantly. However, the median delay for second-line pharmacological treatment was significantly shortened [from 80 min (35-130) in 2002 to 32.5 min (20-75) in 2005]. An increase was observed in the use of surgery for PPH (0.06% versus 0.12% of deliveries; P = 0.03) and in blood transfusions (0.18% versus 0.33%; P = 0.01). The prevalence of major PPH did not change (0.80% versus 0.86% of deliveries; P = 0.62). CONCLUSIONS: The intervention was effective at improving PPH-related preventive and diagnostic practices in a perinatal network. Improving management practices and reducing the prevalence of major PPH might require a different intervention design.
Authors:
E Audureau; C Deneux-Tharaux; P Lefèvre; S Brucato; R Morello; M Dreyfus; M-H Bouvier-Colle
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2009-06-17
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  116     ISSN:  1471-0528     ISO Abbreviation:  BJOG     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-20     Completed Date:  2009-09-30     Revised Date:  2010-01-19    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  1325-33     Citation Subset:  AIM; IM    
Affiliation:
INSERM, UMR S953, Epidemiological Research Unit on Perinatal Health and Women's and Children's Health, UPMC Univ Paris 06, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Abortifacient Agents, Nonsteroidal / administration & dosage
Adult
Clinical Protocols / standards*
Dinoprostone / administration & dosage,  analogs & derivatives
Female
Hospitals, Maternity / standards*
Humans
Infusions, Intravenous
Oxytocics / administration & dosage
Oxytocin / administration & dosage
Postpartum Hemorrhage* / diagnosis,  prevention & control,  surgery
Practice Guidelines as Topic
Pregnancy
Professional Practice / standards*
Prospective Studies
Specimen Handling
Treatment Outcome
Chemical
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 0/Oxytocics; 363-24-6/Dinoprostone; 50-56-6/Oxytocin; 60325-46-4/sulprostone
Comments/Corrections
Comment In:
BJOG. 2010 Feb;117(3):370; author reply 370-1   [PMID:  20078590 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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