Document Detail


Practice patterns for the evaluation and treatment of eosinophilic oesophagitis.
MedLine Citation:
PMID:  21050240     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although consensus guidelines for eosinophilic oesophagitis have been published, it remains unclear whether gastroenterologists follow these recommendations.
AIM: To assess academic and community practice patterns for the evaluation and treatment of eosinophilic oesophagitis and to compare these practices with current guidelines.
METHODS: This was a prospective study of academic and community gastroenterologists using a self-administered online survey.
RESULTS: A total of 60% (34 of 57) of academic and 29% (38 of 133) of community gastroenterologists completed the survey. Only 24% of academic and 3% of community gastroenterologists follow consensus guidelines to diagnose eosinophilic oesophagitis (P = 0.007). A proton pump inhibitor trial or negative pH study prior to diagnosis was required by just 25% of all gastroenterologists. A majority (60%) do not use the recommended threshold of 15 eosinophils per high powered field to diagnosis eosinophilic oesophagitis. Half (51%) mistakenly require a positive endoscopic finding. For first-line treatment, about half of the gastroenterologists surveyed treat with a swallowed topical steroid (53% academic, 56% community; P = N.S.), consistent with the guidelines.
CONCLUSIONS: There is variability in practice patterns for both diagnosis and treatment of eosinophilic oesophagitis. Ongoing education and research concerning diagnosis and treatment are needed.
Authors:
A F Peery; N J Shaheen; E S Dellon
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-10-05
Journal Detail:
Title:  Alimentary pharmacology & therapeutics     Volume:  32     ISSN:  1365-2036     ISO Abbreviation:  Aliment. Pharmacol. Ther.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-05     Completed Date:  2011-02-24     Revised Date:  2011-12-21    
Medline Journal Info:
Nlm Unique ID:  8707234     Medline TA:  Aliment Pharmacol Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  1373-82     Citation Subset:  IM    
Copyright Information:
© 2010 Blackwell Publishing Ltd.
Affiliation:
Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, Chapel Hill, 27599-7080, USA.
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MeSH Terms
Descriptor/Qualifier:
Academic Medical Centers / standards
Adrenal Cortex Hormones / administration & dosage*
Attitude of Health Personnel*
Community Health Services / standards
Esophagitis / physiopathology*,  therapy*
Gastroenterology
Guideline Adherence / standards*
Humans
Internet
Practice Guidelines as Topic
Prospective Studies
Proton Pump Inhibitors / administration & dosage*
Questionnaires
Grant Support
ID/Acronym/Agency:
KL2RR025746/RR/NCRR NIH HHS; T32 DK 07634/DK/NIDDK NIH HHS; T32 DK007634-15/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Proton Pump Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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