| Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice. | |
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MedLine Citation:
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PMID: 16087129 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Surveys of prescribing patterns in both hospitals and primary care have usually shown delays in translating the evidence from clinical trials of pharmacological agents into clinical practice, thereby denying patients with heart failure (HF) the benefits of drug treatments proven to improve well-being and prolong life. This may be due to unfamiliarity with the evidence-base for these therapies, the clinical guidelines recommending the use of these treatments or both, as well as concerns regarding adverse events. ACE inhibitors have long been the cornerstone of therapy for systolic HF irrespective of aetiology. Recent trials have now shown that treatment with beta-blockers, aldosterone antagonists and angiotensin receptor blockers also leads to substantial improvements in outcome. In order to accelerate the safe uptake of these treatments and to ensure that all eligible patients receive the most appropriate medications, a clear and concise set of clinical recommendations has been prepared by a group of clinicians with practical expertise in the management of HF. The objective of these recommendations is to provide practical guidance for non-specialists, in order to increase the use of evidenced based therapy for HF. These practical recommendations are meant to serve as a supplement to, rather than replacement of, existing HF guidelines. |
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Authors:
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John McMurray; Alain Cohen-Solal; Rainer Dietz; Eric Eichhorn; Leif Erhardt; F D Richard Hobbs; Henry Krum; Aldo Maggioni; Robert S McKelvie; Ileana L Piña; Jordi Soler-Soler; Karl Swedberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of heart failure Volume: 7 ISSN: 1388-9842 ISO Abbreviation: Eur. J. Heart Fail. Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-08-09 Completed Date: 2005-12-13 Revised Date: 2013-05-28 |
Medline Journal Info:
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Nlm Unique ID: 100887595 Medline TA: Eur J Heart Fail Country: Netherlands |
Other Details:
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Languages: eng Pagination: 710-21 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Western Infirmary, Glasgow, G12 8QQ, UK. j.mcmurray@bio.gla.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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administration & dosage,
therapeutic use* Angiotensin Receptor Antagonists* Angiotensin-Converting Enzyme Inhibitors / administration & dosage, therapeutic use* Benzimidazoles / administration & dosage, therapeutic use Benzopyrans / administration & dosage, therapeutic use Bisoprolol / administration & dosage, therapeutic use Captopril / administration & dosage, therapeutic use Carbazoles / administration & dosage, therapeutic use Drug Therapy, Combination Enalapril / administration & dosage, therapeutic use Ethanolamines / administration & dosage, therapeutic use Evidence-Based Medicine* Guideline Adherence Heart Failure / drug therapy*, physiopathology Humans Indoles / administration & dosage, therapeutic use Lisinopril / administration & dosage, therapeutic use Metoprolol / administration & dosage, analogs & derivatives, therapeutic use Mineralocorticoid Receptor Antagonists / therapeutic use* Practice Guidelines as Topic* Propanolamines / administration & dosage, therapeutic use Ramipril / administration & dosage, therapeutic use Spironolactone / therapeutic use Stroke Volume Tetrazoles / administration & dosage, therapeutic use Valine / administration & dosage, analogs & derivatives, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Angiotensin Receptor Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Benzimidazoles; 0/Benzopyrans; 0/Carbazoles; 0/Ethanolamines; 0/Indoles; 0/Mineralocorticoid Receptor Antagonists; 0/Propanolamines; 0/Tetrazoles; 030Y90569U/nebivolol; 0K47UL67F2/carvedilol; 137862-53-4/valsartan; 37350-58-6/Metoprolol; 52-01-7/Spironolactone; 62571-86-2/Captopril; 66722-44-9/Bisoprolol; 7004-03-7/Valine; 75847-73-3/Enalapril; 83915-83-7/Lisinopril; 87333-19-5/Ramipril; 87679-37-6/trandolapril; S8Q36MD2XX/candesartan; TH25PD4CCB/metoprolol succinate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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