Document Detail


Practical approach to the treatment of hypothyroidism.
MedLine Citation:
PMID:  1739056     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hypothyroidism most commonly is the result of primary thyroid failure due to autoimmune thyroiditis, but also may follow treated Graves' disease or may occur as transient hypothyroidism. Laboratory evaluation of thyroid function has been refined by the development of ultrasensitive thyroid-stimulating hormone determinations, allowing accurate diagnosis of primary hypothyroidism and assessment of treatment response. Determining whether therapy is appropriate for patients with subclinical hypothyroidism or euthyroid sick syndrome requires clinical judgment in addition to laboratory evaluation. Thyroid hormone replacement for hypothyroidism is best accomplished with levothyroxine. Factors that may affect serum thyroxine levels include thyroid binding globulin levels, drug interactions and variations in thyroxine absorption and clearance.
Authors:
P G Wolf; J C Meek
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American family physician     Volume:  45     ISSN:  0002-838X     ISO Abbreviation:  Am Fam Physician     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-03-17     Completed Date:  1992-03-17     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  722-31     Citation Subset:  AIM; IM    
Affiliation:
University of Kansas School of Medicine-Wichita.
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Hypothyroidism / diagnosis,  drug therapy*,  etiology
Male
Thyroid Gland / physiology

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