Document Detail

Practical application of a low-protein diet for Parkinson's disease.
MedLine Citation:
PMID:  3386817     Owner:  NLM     Status:  MEDLINE    
Thirty-eight patients with Parkinson's disease were treated with a protein-restricted diet in addition to their usual drug regime. Patients who had failed to obtain a significant response to levodopa previously did not benefit. Sixty percent of those with fluctuations in response to levodopa improved, primarily obtaining an increase in the ratio of "on" to "off" hours. Benefit was always noted within a week of diet initiation. The diet was well tolerated with a low incidence of side effects, which could usually be reversed by a reduction in levodopa dosage. A low-protein diet is a simple adjunct to levodopa therapy that can be readily instituted on an outpatient basis. It may improve even those patients with fluctuations who have failed to obtain optimal benefit from all forms of manipulation of the dosage schedule of levodopa or the addition of newer ancillary medications.
D Riley; A E Lang
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurology     Volume:  38     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-03     Completed Date:  1988-08-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1026-31     Citation Subset:  AIM; IM    
Movement Disorders Clinic, Toronto Western Hospital, ON, Canada.
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MeSH Terms
Body Weight
Dietary Proteins*
Levodopa / adverse effects,  therapeutic use
Middle Aged
Parkinson Disease / diet therapy*,  drug therapy
Serum Albumin / analysis
Reg. No./Substance:
0/Dietary Proteins; 0/Levodopa; 0/Serum Albumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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