| A Practical Synthetic Route to Enantiopure 6-Substituted cis-Decahydroquinolines. | |
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MedLine Citation:
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PMID: 22133083 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams. |
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Authors:
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Mercedes Amat; Laura Navío; Núria Llor; Elies Molins; Joan Bosch |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-1 |
Journal Detail:
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Title: Organic letters Volume: - ISSN: 1523-7052 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Laboratory of Organic Chemistry, Faculty of Pharmacy, and Institute of Biomedicine (IBUB), University of Barcelona, 08028-Barcelona, Spain, and Institut de Ciència de Materials de Barcelona (CSIC), Campus UAB, 08193-Cerdanyola, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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