Document Detail


Pr38 pterygium syndrome: a spectrum of features.
MedLine Citation:
PMID:  17490268     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Pterygium Syndrome is an extremely rare and complex congenital disorder consisting of severe contractures involving multiple flexural surfaces and associated craniofacial abnormalities, including mandibular hypoplasia and epicanthic folds. It is also often associated with other congenital abnormalities of the cardiovascular, respiratory and genitourinary systems. It may present in different forms including multiple Pterygium Syndrome of Escobar, lethal multiple Pterygium Syndrome, Popliteal Pterygium Syndrome and Arthrogryposis Multiplex Congenita. The incidence is unknown, a mutation in the IRF6 gene has been found in the Popliteal varient and it is postulated that the pterygia result from the embryonic onset of foetal akinesia. The clinical presentation, multidisciplinary management and longterm outcome of three patients with this condition, managed in the Australian CranioFacial Unit will be presented.
Authors:
N R McLean; S Y Parashar; P J Anderson; M Djohansjah; D J David
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  ANZ journal of surgery     Volume:  77 Suppl 1     ISSN:  1445-1433     ISO Abbreviation:  -     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-05-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101086634     Medline TA:  ANZ J Surg     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  A69     Citation Subset:  IM    
Affiliation:
Australian CranioFacial Institute, South Australia, Australia.
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