Document Detail


Power thrombectomy in acute ischemic coronary syndromes.
MedLine Citation:
PMID:  12934766     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intracoronary thrombi are commonly found in patients with acute coronary syndromes. A large thrombus burden or a platelet-rich thrombus frequently resists pharmacologic therapy ("thrombolytic ceiling"). In such cases restoration of adequate antegrade coronary flow necessitates application of a mechanical force. Power thrombectomy is a revascularization strategy incorporating a mechanical device for removal of occlusive coronary thrombi in conjunction with or following administration of either platelet glycoprotein IIb/IIIa receptor inhibitors or thrombolytic agents, or both. Mechanical devices for power thrombectomy include ultrasound sonication, rheolytic thrombectomy (Angiojet), laser, transluminal extraction catheter, aspiration catheter, and to a limited extent, balloon angioplasty. In acute coronary syndromes the strategy of power thrombectomy aims to achieve the clinical advantages of more nearly complete vessel patency, improved antegrade flow, and enhanced preservation of myocardial tissue.
Authors:
On Topaz; Emerson C Perin; Robert L Jesse; Pramod K Mohanty; Marc Carr; Uri Rosenschein
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  54     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2003 Jul-Aug
Date Detail:
Created Date:  2003-08-25     Completed Date:  2003-09-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  457-68     Citation Subset:  IM    
Affiliation:
Cardiac Catheterization Laboratories, Division of Cardiology, Medical College of Virginia Hospital, Medical College of Virginia/Virginia Commonwealth University, Richmond, VA 23249, USA.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Coronary Thrombosis / complications,  surgery*
Fibrinolytic Agents / therapeutic use
Humans
Male
Middle Aged
Myocardial Ischemia / etiology,  surgery*
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors
Thrombectomy* / instrumentation,  methods
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents; 0/Platelet Glycoprotein GPIIb-IIIa Complex

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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