| Power Doppler sonography to evaluate response to percutaneous ethanol injection in hepatocellular carcinoma. | |
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MedLine Citation:
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PMID: 9513831 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND AIMS: The aim of the present study was to compare power Doppler imaging with traditional color Doppler imaging and with contrast enhanced computer tomography in the evaluation of intratumoral vascularity of hepatocellular carcinomas at diagnosis and in response to percutaneous ethanol injection. PATIENTS AND METHODS: Sixteen patients with hepatocellular carcinoma underwent colour Doppler, power Doppler and computed tomography at diagnosis. Seventeen patients were studied by the three techniques one month after percutaneous ethanol injection treatment. RESULTS: At baseline evaluation, power Doppler and color Doppler were always in agreement and, with the exception of one case, were also in agreement with the computerized tomography scan. On the contrary, power Doppler and computerized tomography are more sensitive than color Doppler in the evaluation of residual vascularized tumoral tissue after percutaneous ethanol injection. In 3 patients, residual vascularity was demonstrated only by computerized tomography while color and power Doppler were negative. In another 3 cases, a positive power Doppler signal, with a typical arterial Doppler spectrum, was observed while color Doppler and computerized tomography were negative. In these patients, cancer relapse was clinically evident after a few months and treatment was repeated to obtain complete necrosis. CONCLUSIONS: We conclude that only the integration of the results of all these techniques can reliably evaluate tumoral vascularity after percutaneous ethanol injection. |
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Authors:
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S Spiezia; P Vallone; F Fiore; P Ricchi; B Daniele; G Picone; G Cerbone; R De Vivo; F Perrone; F Castiglione; S Pignata |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Italian journal of gastroenterology and hepatology Volume: 29 ISSN: 1125-8055 ISO Abbreviation: Ital J Gastroenterol Hepatol Publication Date: 1997 Dec |
Date Detail:
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Created Date: 1998-05-19 Completed Date: 1998-05-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9711056 Medline TA: Ital J Gastroenterol Hepatol Country: ITALY |
Other Details:
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Languages: eng Pagination: 548-53 Citation Subset: IM |
Affiliation:
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Surgery Unit, Incurabili Hospital, Naples, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma, Hepatocellular / diagnosis, drug therapy*, ultrasonography* Contrast Media Ethanol / administration & dosage* Female Follow-Up Studies Humans Injections, Subcutaneous Liver / blood supply, ultrasonography Liver Neoplasms / diagnosis, drug therapy*, ultrasonography* Male Microcirculation / ultrasonography Middle Aged Prognosis Radiographic Image Enhancement Sensitivity and Specificity Tomography, X-Ray Computed / methods* Ultrasonography, Doppler* Ultrasonography, Doppler, Color |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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