Document Detail


Power Doppler evaluation of joint effusions: investigation in a rabbit model.
MedLine Citation:
PMID:  10415191     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the power Doppler findings of septic arthritis and noninfectious synovitis in an animal model. MATERIALS AND METHODS: The right knees of 10 rabbits were inoculated with an aqueous suspension of Staphylococcus aureus. The right knees of 5 rabbits were injected with talc suspension. The right knees of 5 rabbits were injected with saline. All 20 left knees were injected with saline. Serial power Doppler images were obtained using constant-imaging parameters. Images were reviewed by blinded observers who assessed for increased power Doppler signal. RESULTS: All 10 knees inoculated with S. aureus developed septic arthritis. Each infected rabbit knee demonstrated increased signal on power Doppler on at least one examination, ranging from 1-6 days after inoculation. Only 23 of 45 examinations of infected knees were unequivocally positive by power Doppler on examinations performed 1 to 6 days after inoculation. No knee with talc synovitis demonstrated increased power Doppler signal. No control knee demonstrated increased power Doppler signal. CONCLUSION: Increased power Doppler signal may be seen with septic arthritis; however, its intensity and timing may vary from subject to subject. A normal power Doppler examination does not exclude septic arthritis.
Authors:
P J Strouse; M A DiPietro; E L Teo; K Doi; C E Chrisp
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric radiology     Volume:  29     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-09-30     Completed Date:  1999-09-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  617-23     Citation Subset:  IM    
Affiliation:
Division of Pediatric Radiology, C. S. Mott Children's Hospital, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0252, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Arthritis, Infectious / ultrasonography*
Disease Models, Animal
Exudates and Transudates
Image Processing, Computer-Assisted
Knee / microbiology,  pathology
Rabbits
Sensitivity and Specificity
Staphylococcal Infections / ultrasonography*
Staphylococcus aureus
Synovial Membrane / microbiology,  pathology*
Synovitis / chemically induced,  microbiology,  ultrasonography*
Talc
Ultrasonography, Doppler*
Chemical
Reg. No./Substance:
14807-96-6/Talc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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