Document Detail


Potentiometric titrations in a poly(dimethylsiloxane)-based microfluidic device.
MedLine Citation:
PMID:  15080738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper describes a microfluidic device, fabricated in poly(dimethylsiloxane), that is used for potentiometric titrations. This system generates step gradients of redox potentials in a series of microchannels. These potentials are probed by microelectrodes that are integrated into the chip; the measured potentials were used to produce a titration curve from which the end point of a reaction was measured.
Authors:
Rosaria Ferrigno; Jessamine Ng Lee; Xingyu Jiang; George M Whitesides
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Analytical chemistry     Volume:  76     ISSN:  0003-2700     ISO Abbreviation:  Anal. Chem.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-04-14     Completed Date:  2005-02-01     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370536     Medline TA:  Anal Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2273-80     Citation Subset:  IM    
Affiliation:
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
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MeSH Terms
Descriptor/Qualifier:
Dimethylpolysiloxanes / chemistry*
Electrodes
Microfluidics / instrumentation,  methods*
Platinum / chemistry
Potentiometry / methods
Silicones / chemistry*
Grant Support
ID/Acronym/Agency:
GM65364/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Dimethylpolysiloxanes; 0/Silicones; 63148-62-9/baysilon; 7440-06-4/Platinum

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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