| Potentiation of pathogen-specific defense mechanisms in Arabidopsis by beta -aminobutyric acid. | |
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MedLine Citation:
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PMID: 11058166 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The nonprotein amino acids gamma-aminobutyric acid (GABA) and beta-aminobutyric acid (BABA) have known biological effects in animals and plants. Their mode of action has been the object of thorough research in animals but remains unclear in plants. Our objective was to study the mode of action of BABA in the protection of Arabidopis plants against virulent pathogens. BABA protected Arabidopsis against the oomycete pathogen Peronospora parasitica through activation of natural defense mechanisms of the plant such as callose deposition, the hypersensitive response, and the formation of trailing necroses. BABA was still fully protective against P. parasitica in transgenic plants or mutants impaired in the salicylic acid, jasmonic acid, and ethylene signaling pathways. Treatment with BABA did not induce the accumulation of mRNA of the systemic acquired resistance (SAR)-associated PR-1 and the ethylene- and jasmonic acid-dependent PDF1.2 genes. However, BABA potentiated the accumulation of PR-1 mRNA after attack by virulent pathogenic bacteria. As a result, BABA-treated Arabidopsis plants were less diseased compared with the untreated control. In the case of bacteria, BABA protected mutants insensitive to jasmonic acid and ethylene but was not active in plants impaired in the SAR transduction pathway. Thus, BABA protects Arabidopsis against different virulent pathogens by potentiating pathogen-specific plant resistance mechanisms. In addition, we provide evidence that BABA-mediated papilla formation after P. parasitica infection is independent of the SAR signaling pathway. |
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Authors:
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L Zimmerli; G Jakab; J P Metraux; B Mauch-Mani |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 97 ISSN: 0027-8424 ISO Abbreviation: Proc. Natl. Acad. Sci. U.S.A. Publication Date: 2000 Nov |
Date Detail:
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Created Date: 2000-11-27 Completed Date: 2001-01-11 Revised Date: 2010-09-14 |
Medline Journal Info:
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Nlm Unique ID: 7505876 Medline TA: Proc Natl Acad Sci U S A Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 12920-5 Citation Subset: IM |
Affiliation:
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Department of Biology, Plant Biology, University of Fribourg, Route Albert Gockel 3, 1700 Fribourg, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aminobutyric Acids
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metabolism* Arabidopsis / microbiology* Oomycetes / pathogenicity* Plant Diseases Plants, Genetically Modified Pseudomonas / pathogenicity |
| Chemical | |
Reg. No./Substance:
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0/Aminobutyric Acids; 541-48-0/3-aminobutyric acid |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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