| Potentiation of the action of warfarin by bezafibrate in patients with the nephrotic syndrome. | |
| | |
MedLine Citation:
|
PMID: 18583756 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Nephrotic syndrome is associated with thromboembolic disease due to a variety of factors. In addition, therapy with anticoagulants is often met with poor response, to warfarin for example, which occurs due to factors such as reduced serum albumin and binding sites, increased free warfarin with rapid metabolism and clearance, and possible urinary loss. Bezafibrate is known to augment the action of warfarin and improve coagulation profile. In this article, we present three cases with severe nephrotic syndrome associated with hyperfibrinogenemia, hypercholesterolemia and thromboembolic disease who showed poor response to therapy with warfarin. They showed improvement of their coagulation profile upon concomitant administration of bezafibrate. |
| | |
Authors:
|
A K Al-Momen; H Al-Abdul-Kareem |
Related Documents
:
|
19279126 - Loss of podocyte apkclambda/iota causes polarity defects and nephrotic syndrome. 2267216 - Hepatic infarction: an unusual complication of nephrotic syndrome in a patient with dia... 10444806 - Nephrotic syndrome and acute interstitial nephritis associated with the use of diclofenac. 2115146 - Henoch-schönlein purpura after salmonella hirschfeldii infection. 19037986 - Postural orthostatic tachycardia in a teenager with klinefelter syndrome. 20380896 - Cytosolic calcium accumulation and delayed repolarization associated with ventricular a... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia Volume: 5 ISSN: 1319-2442 ISO Abbreviation: Saudi J Kidney Dis Transpl Publication Date: 1994 January-March |
Date Detail:
|
Created Date: 2008-06-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9436968 Medline TA: Saudi J Kidney Dis Transpl Country: Saudi Arabia |
Other Details:
|
Languages: eng Pagination: 12-6 Citation Subset: - |
Affiliation:
|
Division of Hematology, Department of Medicine, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Monitoring of glomerulonephritis.
Next Document: Acute Renal Failure due to Rhabdomyolysis Following Human Stampede.