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Potentially inappropriate medication use in Indian elderly: Comparison of Beers' criteria and Screening Tool of Older Persons' potentially inappropriate Prescriptions.
MedLine Citation:
PMID:  22239067     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aim:  To compare Beers' criteria (BC) and Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) for prevalence, specificity, sensitivity and predictors for potentially inappropriate medication (PIM) use. Methods:  Patients aged ≥60 years from medicine wards of a tertiary care hospital were included. Comparisons between BC and STOPP were made using Pearson's χ(2) -test for categorical variables and Mann-Whitney U-test for continuous variables. Specificity and sensitivity were assessed by using 2 × 2 contingency table. Bivariate analysis and subsequent multivariate logistic regression was used to identify the predictors of PIM use. Results:  In the 540 patients included, prevalence of PIM use as per BC and STOPP was 24.6% and 13.3%, respectively. Sensitivity and specificity of BC in detecting PIM was 0.65 and 0.53, respectively. Considering the diagnoses/conditions, sensitivity and specificity of BC was 0.12 and 0.48, respectively, whereas independent of diagnoses/conditions, corresponding values were 0.75 and 0.54. PIM as per BC and STOPP accounted for 11 and 6 adverse drug reactions (ADR), respectively. Medications not listed in BC or STOPP were more likely to be associated with ADR. Multiple diseases (≥4) and use of more drugs during hospital stay (10-14) predicted PIM use as per BC, whereas age (60-74 years) predicted PIM use as per STOPP. Conclusion:  Overall, BC is useful in the detection of PIM use independent of diagnoses/conditions, whereas STOPP is useful in detection of PIM use considering the diagnoses/conditions. There is a need for consensus on using the tool for detection of PIM use in Indian elderly. Geriatr Gerontol Int 2012; ••: ••-••.
Authors:
Hunsur Nagendra Vishwas; Anand Harugeri; Gurumurthy Parthasarathi; Madhan Ramesh
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-12
Journal Detail:
Title:  Geriatrics & gerontology international     Volume:  -     ISSN:  1447-0594     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101135738     Medline TA:  Geriatr Gerontol Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Japan Geriatrics Society.
Affiliation:
Department of Pharmacy Practice, JSS College of Pharmacy Department of Clinical Pharmacy, JSS Medical College Hospital, JSS University, Mysore, India.
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