Document Detail

Potential strategies to improve uptake of exercise interventions in non-alcoholic fatty liver disease.
MedLine Citation:
PMID:  19897272     Owner:  NLM     Status:  MEDLINE    
BACKGROUND & AIMS: The management of non-alcoholic liver disease (NAFLD) concerns lifestyle modification and exercise; however, adherence is poor. Factors such as lack of confidence to exercise, poor understanding of the benefits of exercise, and a fear of falling all influence engagement in physical activity. To increase exercise in NAFLD it is important to understand the barriers to performing it.
METHODS: Three chronic liver disease cohorts were identified from the Newcastle Liver Database: NAFLD (n=230), alcoholic liver disease (ALD, n=110) and primary biliary cirrhosis (PBC, n=97). Assessment tools were completed by all subjects: Outcome Expectation for Exercise Scale (OEES, understanding the benefits of exercise, lower scores indicate greater understanding), Self-Efficacy for Exercise Scale (SEES, confidence to exercise), Falls Efficacy Scale-International (FES-I, higher scores indicate greater fear of falling). Activity was analysed from a functional perspective using the PROMIS-HAQ.
RESULTS: Understanding the benefits of exercise was similar across each group [median OEES scores: NAFLD 2.38 (range 0.0-5.0), ALD 2.25 (0.0-5.0), PBC 2.28 (1.0-5.0), p=0.6]. In NAFLD confidence to exercise was significantly lower [median SEES score 0.0 (0.0-10.0), PBC 4.5 (0.0-10.0), p<0.001]. Fear of falling was similar in NAFLD and PBC, and greatest in ALD [22 (0-64), 22 (3-64), 30 (0-64), p=0.044]. In NAFLD, fear of falling was independently associated with increasing difficulty performing activity.
CONCLUSIONS: NAFLD patients understand the benefits of exercise but lack confidence to perform it. Fear of falling was independently associated with more difficulty performing activity. Fear of falling and confidence are modifiable and potential targets to improve uptake and adherence for exercise intervention.
James Frith; Christopher P Day; Lisa Robinson; Chris Elliott; David E J Jones; Julia L Newton
Publication Detail:
Type:  Journal Article     Date:  2009-10-23
Journal Detail:
Title:  Journal of hepatology     Volume:  52     ISSN:  1600-0641     ISO Abbreviation:  J. Hepatol.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-09-16     Revised Date:  2014-02-19    
Medline Journal Info:
Nlm Unique ID:  8503886     Medline TA:  J Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  112-6     Citation Subset:  IM    
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MeSH Terms
Accidental Falls
Case-Control Studies
Cohort Studies
Exercise / psychology*
Fatty Liver / therapy*
Fatty Liver, Alcoholic
Life Style
Liver Cirrhosis, Biliary
Middle Aged
Patient Compliance / psychology*
Self Efficacy
Grant Support
G0500020//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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