| Potential role of high-field MRI for studies in Parkinson's disease. | |
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MedLine Citation:
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PMID: 19877239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent advancements in high field magnetic resonance imaging (MRI) technology (3 T and higher), providing increased signal sensitivity and images with more prominent contrasts intrinsic to the brain, offer new opportunities for assessing brain alterations in Parkinson's disease (PD). In this article, the principle benefits of high field MRI for PD research are described and new findings at high magnetic fields are reviewed. Several high field MRI methodologies, including structural MRI, imaging of brain iron, diffusion tensor imaging, arterial spin labeling perfusion imaging, rotating frame imaging, and magnetic resonance spectroscopy, are critically reviewed for their potential roles in studies of PD. |
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Authors:
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Norbert Schuff |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 24 Suppl 2 ISSN: 1531-8257 ISO Abbreviation: Mov. Disord. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-11-05 Completed Date: 2010-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: United States |
Other Details:
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Languages: eng Pagination: S684-90 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Movement Disorder Society |
Affiliation:
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Centre for Imaging of Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, California 94121, USA. norbert.schuff@ucsf.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain Chemistry Cerebrovascular Circulation / physiology Diffusion Magnetic Resonance Imaging Humans Iron / chemistry, metabolism Magnetic Resonance Imaging / methods* Magnetic Resonance Spectroscopy Parkinson Disease / pathology*, physiopathology Spin Labels |
| Chemical | |
Reg. No./Substance:
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0/Spin Labels; 7439-89-6/Iron |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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