| Potential risks and benefits of antenatal corticosteroid therapy prior to preterm birth in pregnancies complicated by severe fetal growth restriction. | |
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MedLine Citation:
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PMID: 21575796 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The antepartum administration of fluorinated corticosteroids for fetal maturation represents the most important clinical contribution in the battle against prematurity. This treatment reduces the risk of neonatal death and handicap. It is also known that on corticosteroid exposure, fetuses are subjected to transiently increased physiologic and metabolic demands. Healthy fetuses are able to cope, although emerging evidence suggests this may not be the case with severely growth-restricted fetuses. This review presents evidence of efficacy and safety pertaining to corticosteroid administration in fetal growth restriction-affected pregnancies, offers guidance to clinicians, and points out questions that still need answers. |
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Authors:
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Alex C Vidaeff; Sean C Blackwell |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology clinics of North America Volume: 38 ISSN: 1558-0474 ISO Abbreviation: Obstet. Gynecol. Clin. North Am. Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-05-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8709551 Medline TA: Obstet Gynecol Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 205-14 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Medical School at Houston, 6431 Fannin Street, Suite 3.283, Houston, TX 77030, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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