Document Detail

Potential of the right ventricular endomyocardial biopsy to diagnose and assist in the management of congestive heart failure: insights from recent clinical trials.
MedLine Citation:
PMID:  15184727     Owner:  NLM     Status:  MEDLINE    
In the United States congestive heart failure is most commonly due to ischemic cardiomyopathy, but nonischemic causes of cardiomyopathy can also result in congestive heart failure. Indeed, nonischemic dilated cardiomyopathy affects approximately 100,000 persons in the United States and is responsible for 45% of heart transplants. Although these patients undergo thorough cardiovascular evaluation, a specific cause is usually not found. Endomyocardial biopsy may yield diagnostic and prognostic information in this setting, and there has been a renewed interest in the use of endomyocardial biopsy in the evaluation of specific subsets of patients with congestive heart failure to identify potentially treatable myocarditides. However, the role of endomyocardial biopsy in the evaluation of patients with nonischemic cardiomyopathy is ill defined. In this review, the authors discuss the latest data on the risks and the utility of endomyocardial biopsy in the management of heart failure in the setting of dilated cardiomyopathy and specific myocarditides. Gaps in present knowledge and the obstacles to research in this area are identified.
Lambert Wu; Leslie Cooper
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Congestive heart failure (Greenwich, Conn.)     Volume:  10     ISSN:  1527-5299     ISO Abbreviation:  Congest Heart Fail     Publication Date:    2004 May-Jun
Date Detail:
Created Date:  2004-06-08     Completed Date:  2004-09-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9714174     Medline TA:  Congest Heart Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  133-9     Citation Subset:  IM    
Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
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MeSH Terms
Biopsy* / adverse effects,  methods
Cardiomyopathy, Dilated / complications,  diagnosis*
Clinical Protocols
Clinical Trials as Topic
Diagnosis, Differential
Heart Failure / diagnosis*,  etiology
Heart Ventricles / pathology*
Myocarditis / complications,  diagnosis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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