| Potential and limitations of advanced MRI and CT. | |
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MedLine Citation:
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PMID: 22185911 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Radiotherapy has been considerably improved by three-dimensional intensity-modulated radiation therapy (imRT). The technique of dose painting affords precise adaption of the dose distribution to the complex geometry of the tumor including an improved block out of surrounding healthy structures. Progress in image-guided radiotherapy enables tracking of tumor and healthy organs repeatedly before or even during each treatment session, thereby taking account temporal changes of tumor positions due to organ movement or tumor geometry caused by treatment effects. Adequate registration of the tumor localization, its heterogeneous viability and temporal variations during radiotherapy enable optimization of radiotherapy treatment effects by concurrently preserving adjacent healthy tissue. In this context, the actual treatment success depends on the capability of oncologic imaging tools to precisely localize and delineate the tumor and provide information about its biologic and functional heterogeneity. Oncologic imaging is accordingly challenged to improve and further develop novel concepts for precise tumor delineation and biologic/functional tumor characterization as well as for recording temporal changes to repeatedly adapt an individual radiotherapy treatment plan. Important progress has been achieved by multiparametric and multimodal imaging approaches including morphologic functional imaging by computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET)/CT and recently PET/MR. One major challenge is to incorporate progress in quantitative imaging technology into radiotherapy treatment planning, guidance and monitoring. This presentation reviews the potential and limitations of advanced techniques and technologies of MRI and CT that support novel radiotherapy concepts. |
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Authors:
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H-P Schlemmer |
Publication Detail:
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Type: Journal Article Date: 2011-10-03 |
Journal Detail:
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Title: Cancer imaging : the official publication of the International Cancer Imaging Society Volume: 11 ISSN: 1470-7330 ISO Abbreviation: Cancer Imaging Publication Date: 2011 |
Date Detail:
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Created Date: 2011-12-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101172931 Medline TA: Cancer Imaging Country: England |
Other Details:
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Languages: eng Pagination: S153 Citation Subset: IM |
Affiliation:
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Department of Radiology, German Cancer Research Center, Heidelberg, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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