| Potential influence of pre-infarction angina on myocardial viability and residual ischemia. | |
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MedLine Citation:
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PMID: 11392639 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The effects of recent pre-infarction angina on myocardial viability and residual ischemia are unknown. This study evaluates them in 90 patients with a first Q-wave myocardial infarction using early dobutamine stress echocardiography. METHODS: Patients were classified according to the absence or presence of recent pre-infarction angina, defined as chest pain lasting < 30 min during a period of 7 days before the acute myocardial infarction. The infarct zone wall motion score index was calculated at baseline and at low- and peak-dose dobutamine stress echocardiography. All subjects underwent coronary angiography. RESULTS: Patients with unheralded myocardial infarction showed, in comparison with patients with recent pre-infarction angina, a significantly higher peak of creatine kinase serum levels (2630 +/- 1360 vs 1865 +/- 1562 IU/l, p = 0.002) and a higher number of leads with pathologic Q waves (3.2 +/- 1.3 vs 2.8 +/- 0.8, p = 0.002). The groups did not differ with regard to the infarct zone wall motion score index at rest (2.15 +/- 0.42 vs 2.18 +/- 0.31, p = 0.72) and at low- (1.86 +/- 0.52 vs 1.80 +/- 0.41, p = 0.55) and peak-dose (2.24 +/- 0.55 vs 2.19 +/- 0.58, p = 0.68) dobutamine stress echocardiography. The prevalence of myocardial viability (31 vs 48%, p = 0.15), homozonal (52 vs 58%, p = NS) or heterozonal ischemia (36 vs 23%, p = NS) was not statistically different between the groups of patients without and with recent pre-infarction angina. The angiographic patterns were similar. CONCLUSIONS: Recent pre-infarction angina is associated with a smaller infarct size but it does not seem to influence the ventricular contractile improvement or residual ischemia, detected at early dobutamine echocardiography, in patients with a first Q-wave myocardial infarction. |
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Authors:
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F De Felice; E Gostoli; M Russo; P Recanzone; C Moretti; F Pinneri; G Borello |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Italian heart journal : official journal of the Italian Federation of Cardiology Volume: 2 ISSN: 1129-471X ISO Abbreviation: Ital Heart J Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-06-05 Completed Date: 2001-10-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100909716 Medline TA: Ital Heart J Country: Italy |
Other Details:
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Languages: eng Pagination: 356-62 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Civic Hospital of Chivasso, TO, Italy. f.defelice@eudoramail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / complications*, radiography, ultrasonography Coronary Angiography Dobutamine / diagnostic use Echocardiography Electrocardiography Exercise Test / methods Female Humans Male Middle Aged Myocardial Infarction / etiology, radiography, ultrasonography Myocardial Ischemia / etiology*, radiography, ultrasonography Risk Factors Stroke Volume / physiology |
| Chemical | |
Reg. No./Substance:
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34368-04-2/Dobutamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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