Document Detail

Potential for effects of land contamination on human health. 2. The case of waste disposal sites.
MedLine Citation:
PMID:  23190269     Owner:  NLM     Status:  In-Data-Review    
This review of the epidemiological literature shows that evidence for negative impacts of land contaminated by waste disposal on human health is limited. However, the potential for health impacts cannot be dismissed. The link between residence close to hazardous waste disposal sites and heightened levels of stress and anxiety is relatively well established. However, studies on self-reported outcomes generally suffer from interpretational problems, as subjective symptoms may be due to increased perception and recall. Several recent multiple-site studies support a plausible linkage between residence near waste disposal sites and reproductive effects (including congenital anomalies and low birth weight). There is some conflict in the literature investigating links between land contamination and cancers; the evidence for and against a link is equally balanced and is insufficient to make causal inferences. These are difficult to establish because of lack of data on individual exposures, and other socioeconomic and lifestyle factors that may confound a relationship with area of residence. There is no consistently occurring risk for any specific tumor across multiple studies on sites expected to contain similar contaminants. Further insights on health effects of land contamination are likely to be gained from studies that consider exposure pathways and biomarkers of exposure and effect, similar to those deployed with some success in investigating impacts of cadmium on human health.
Melanie Kah; Len Levy; Colin Brown
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of toxicology and environmental health. Part B, Critical reviews     Volume:  15     ISSN:  1521-6950     ISO Abbreviation:  J Toxicol Environ Health B Crit Rev     Publication Date:  2012  
Date Detail:
Created Date:  2012-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9802627     Medline TA:  J Toxicol Environ Health B Crit Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  441-67     Citation Subset:  IM    
a Department of Environmental Geosciences , University of Vienna , Vienna , Austria.
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