Document Detail


Potential effects of dietary folate supplementation on oral carcinogenesis, development and progression.
MedLine Citation:
PMID:  22435573     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
ABSTRACT. Folates are associated with a variety of human health benefits, while folate deficiency has been identified as a potential risk factor for many health problems and cancers, due to its role in dysregulation of DNA synthesis, repair and methylation. The US Food and Drug Administration adopted requirements for folate fortification in some food products, which has resulted in an increase in mean dietary folate intake and a concomitant reduction in the incidence of adverse health effects associated with folate deficiency. This includes a significant reduction in the incidence of folate deficiency-associated birth defects, such as spina bifida.
Authors:
Karl Kingsley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of dietary supplements     Volume:  7     ISSN:  1939-0211     ISO Abbreviation:  J Diet Suppl     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2012-03-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101249830     Medline TA:  J Diet Suppl     Country:  England    
Other Details:
Languages:  eng     Pagination:  51-9     Citation Subset:  IM    
Affiliation:
Karl Kingsley is Assistant Professor of Biomedical Sciences, University of Nevada, Las Vegas - School of Dental Medicine, 1001 Shadow Lane, B315, Las Vegas, NV 89106.
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