| Potential dietary exposure to p-nonylphenol from food-contact use of tris(nonylphenyl)phosphite (TNPP). | |
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MedLine Citation:
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PMID: 11665731 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The potential exposure to p-nonylphenol from the use of tris(nonylphenyl)phosphite (TNPP) in food-contact materials was calculated. The calculation was made on the basis of migration data from moulded plaques prepared from linear low-density polyethylene (LLDPE), films prepared from LLDPE and polyvinyl chloride (PVC) films. The data were obtained using the customary expermental procedures developed by the US Food and Drug Administration (FDA). The potential migration of p-nonylphenol to food from the use of TNPP as a component of food-contact articles was determined using food-simulating solvents and time and temperature conditions recommended by the FDA. Using the data obtained from these studies, along with procedures based on the FDA's conventional method for estimating potential dietary exposure using food simulating migration data, the potential dietary exposure to p-nonylphenol from the use of TNPP was determined to be approximately 25.5 parts per billion (ppb). Because the conditions of the migration tests exaggerate actual use conditions, this value overstates the potential dietary exposure. |
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Authors:
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S R Howe; P Surana; M R Jakupca; L Borodinsky |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Food additives and contaminants Volume: 18 ISSN: 0265-203X ISO Abbreviation: Food Addit Contam Publication Date: 2001 Nov |
Date Detail:
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Created Date: 2001-10-22 Completed Date: 2001-12-04 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8500474 Medline TA: Food Addit Contam Country: England |
Other Details:
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Languages: eng Pagination: 1021-39 Citation Subset: IM |
Affiliation:
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Worker and Product Safety, The Society of the Plastics Industry, Inc., Washington, DC 20006-1301, USA. showe@socplas.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromatography, High Pressure Liquid Food Contamination* Food Packaging* Humans Phenols / pharmacokinetics* Polyethylenes / chemistry Polyvinyl Chloride / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Phenols; 0/Polyethylenes; 25154-52-3/nonylphenol; 9002-86-2/Polyvinyl Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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