Document Detail

Potential for altering rheumatoid arthritis outcome.
MedLine Citation:
PMID:  16287596     Owner:  NLM     Status:  MEDLINE    
The potential for disproportionately altering outcome in the early stages of rheumatoid arthritis (RA) was first hypothesized in the early 1990s. This window of opportunity hypothesis for therapeutic intervention in RA is based on the existence of a time frame within which there is a potential for a greater response to therapy, resulting in sustained benefits or, perhaps most important, a chance of cure. Given the persistent, progressive, damaging, inflammatory nature of RA, this approach to altering outcome in the early stages seems attractive.
Mark A Quinn; Paul Emery
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Rheumatic diseases clinics of North America     Volume:  31     ISSN:  0889-857X     ISO Abbreviation:  Rheum. Dis. Clin. North Am.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-18     Completed Date:  2006-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708093     Medline TA:  Rheum Dis Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  763-72     Citation Subset:  IM    
Academic Unit of Musculoskeletal Disease, Department of Rheumatology, Chapel Allerton Hospital, 2nd Floor, Chapel Town Road, Leeds LS7 4SA, UK.
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MeSH Terms
Antirheumatic Agents / therapeutic use*
Arthritis, Rheumatoid / diagnosis*,  drug therapy*
Early Diagnosis
Treatment Outcome
Reg. No./Substance:
0/Antirheumatic Agents

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