| Potential adverse drug events in an indigent and homeless geriatric population. | |
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MedLine Citation:
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PMID: 11675839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To identify potential adverse drug events (ADEs) in a geriatric ambulatory population using the modified Beers criteria. METHODS: This is a cross-sectional study of an indigent and homeless geriatric population served by a network of six primary healthcare clinics with clinical pharmacy services. Medical records of patients > or = 65 years old visiting the clinics between December 1999 and April 2000 were retrospectively reviewed by a clinical pharmacist. Medications meeting the modfied Beers criteria were evaluated for the most common drug classes involved, severity potential, and dose or disease state restrictions. Following the identification of medications meeting Beers criteria, the pharmacist left a written recommendation regarding use of alternative drugs or doses in the medical record. Physician acceptance of pharmacy recommendations was also evaluated. RESULTS: Medical records of 146 patients (71.9% women, average age 72.6 +/- 6.7 y) were reviewed. Overall, 52 patients (35.6%) had 70 medications with the potential for causing an ADE based on the modified Beers criteria The most commonly identified medication classes were narcotic analgesics (20.0%), antihypertensives (20.0%), and antihistamines (14.3%). Fifteen of these medications (21.4%) had a high severity potential. Identified medications met the following modified Beers criteria: 41.4% were inappropriate in a specific disease state, 38.6% were inappropriate for the elderly, 10.0% exceeded maximum dosage guidelines, and 10.0% were inappropriate for both the elerly and the patients disease state. Approximately 60% of pharmacy recommendations were accepted by physicians. CONCLUSIONS: The modified Beers criteria are a useful tool for reviewing medical records to identify potential ADEs in an ambulatory geriatric population. |
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Authors:
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E C Spiker; R E Emptage; M R Giannamore; C A Pedersen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of pharmacotherapy Volume: 35 ISSN: 1060-0280 ISO Abbreviation: Ann Pharmacother Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-10-24 Completed Date: 2002-03-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9203131 Medline TA: Ann Pharmacother Country: United States |
Other Details:
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Languages: eng Pagination: 1166-72 Citation Subset: IM |
Affiliation:
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College of Pharmacy, The Ohio State University, Columbus 43210-1291, USA. spiker.10@osu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Ambulatory Care / statistics & numerical data* Cross-Sectional Studies Drug Therapy / adverse effects* Female Geriatrics* Homeless Persons* Humans Male Medical Records Ohio Poverty / statistics & numerical data* Retrospective Studies |
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