Document Detail


Potential of CT angiography in acute ischemic stroke.
MedLine Citation:
PMID:  9194425     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To study the ability of CT angiography to show intracranial arterial occlusion and collateral blood flow in patients with acute stroke. METHODS: Twenty-one patients with acute nonhemorrhagic stroke were studied prospectively with conventional CT, CT angiography, and digital subtraction angiography. On the basis of CT angiographic findings, two neuroradiologists independently assessed the site of arterial occlusion, the contrast enhancement in arterial branches beyond the occlusion as a measure of collateral blood supply, and the extent of diminished parenchymal enhancement; they then predicted the extent of ischemic infarction. RESULTS: Both raters correctly assessed all trunk occlusions of the basilar artery (n = 4), the internal carotid artery (n = 4), and the middle cerebral artery (n = 9). The chance adjusted interrater agreement was kappa = .78. The assessment of branch occlusions of the middle cerebral artery was less reliable. The agreement rate in judging the collateral state in 17 occlusions in the anterior cerebral circulation was 88%. The size of 21 (62%) of 34 hemispheric infarctions was predicted correctly. CONCLUSION: CT angiography quickly and reliably adds important information to conventional CT studies in cases of acute ischemic stroke. It shows the site of occlusion, the length of the occluded arterial segment, and the contrast-enhanced arteries beyond the occlusion as an estimate of collateral blood flow.
Authors:
M Knauth; R von Kummer; O Jansen; S Hähnel; A Dörfler; K Sartor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  18     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:    1997 Jun-Jul
Date Detail:
Created Date:  1997-08-19     Completed Date:  1997-08-19     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1001-10     Citation Subset:  IM    
Affiliation:
Department of Neuroradiology, University of Heidelberg Medical School, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angiography, Digital Subtraction / instrumentation
Brain / blood supply
Brain Ischemia / radiography*
Cerebral Angiography / instrumentation*
Cerebral Infarction / radiography
Cerebrovascular Disorders / radiography*
Collateral Circulation / physiology
Diagnosis, Differential
Female
Humans
Image Processing, Computer-Assisted / instrumentation*
Male
Meninges / blood supply
Middle Aged
Sensitivity and Specificity
Tomography, X-Ray Computed / instrumentation*
Vertebrobasilar Insufficiency / radiography
Comments/Corrections
Comment In:
AJNR Am J Neuroradiol. 1997 Jun-Jul;18(6):1021-3   [PMID:  9194427 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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