Document Detail

Potassium supplementation in blacks with mild to moderate essential hypertension.
MedLine Citation:
PMID:  3514747     Owner:  NLM     Status:  MEDLINE    
Potassium chloride (KCl) salt (65 mmol) daily reduced BP from 153/104 to 146/101 mmHg in 32 hypertensive black females during a 6-week placebo controlled crossover study. The fall in BP was independent of the order of randomization and was significant for systolic (SBP; P less than 0.01) and diastolic (DBP; P less than 0.05) pressure after 4 weeks. Analysis of the 95% confidence intervals in this and in five other studies, two of which were reported as showing no beneficial effect, suggests that potassium supplementation does lower BP, but that the change is small and within the confidence levels of all six trials. Thus, apparent discrepancies in the literature are not genuine statistically.
S M Matlou; C G Isles; A Higgs; F J Milne; G D Murray; E Schultz; I F Starke
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension     Volume:  4     ISSN:  0263-6352     ISO Abbreviation:  J. Hypertens.     Publication Date:  1986 Feb 
Date Detail:
Created Date:  1986-05-07     Completed Date:  1986-05-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  61-4     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / drug effects
Clinical Trials as Topic
Hypertension / drug therapy*,  physiopathology
Middle Aged
Potassium / blood,  urine
Potassium Chloride / therapeutic use*
Random Allocation
Sodium / urine
Reg. No./Substance:
7440-09-7/Potassium; 7440-23-5/Sodium; 7447-40-7/Potassium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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