| Potassium supplementation in blacks with mild to moderate essential hypertension. | |
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MedLine Citation:
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PMID: 3514747 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Potassium chloride (KCl) salt (65 mmol) daily reduced BP from 153/104 to 146/101 mmHg in 32 hypertensive black females during a 6-week placebo controlled crossover study. The fall in BP was independent of the order of randomization and was significant for systolic (SBP; P less than 0.01) and diastolic (DBP; P less than 0.05) pressure after 4 weeks. Analysis of the 95% confidence intervals in this and in five other studies, two of which were reported as showing no beneficial effect, suggests that potassium supplementation does lower BP, but that the change is small and within the confidence levels of all six trials. Thus, apparent discrepancies in the literature are not genuine statistically. |
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Authors:
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S M Matlou; C G Isles; A Higgs; F J Milne; G D Murray; E Schultz; I F Starke |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of hypertension Volume: 4 ISSN: 0263-6352 ISO Abbreviation: J. Hypertens. Publication Date: 1986 Feb |
Date Detail:
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Created Date: 1986-05-07 Completed Date: 1986-05-07 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8306882 Medline TA: J Hypertens Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 61-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Pressure / drug effects Clinical Trials as Topic Female Humans Hypertension / drug therapy*, physiopathology Middle Aged Potassium / blood, urine Potassium Chloride / therapeutic use* Random Allocation Sodium / urine |
| Chemical | |
Reg. No./Substance:
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7440-09-7/Potassium; 7440-23-5/Sodium; 7447-40-7/Potassium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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