Document Detail


Postural orthostatic tachycardia in a teenager with Klinefelter syndrome.
MedLine Citation:
PMID:  19037986     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To our knowledge this is the first reported case of postural orthostatic tachycardia syndrome (POTS) in a patient with Klinefelter syndrome. We describe a classic clinical presentation of POTS in an adolescent male with Klinefelter syndrome. Although the etiology of POTS appears to be multifactorial, there is a strong female predominance that suggests a genetic basis. Our patient with Klinefelter syndrome may further support a link with POTS to the X chromosome.
Authors:
Michael R Hainstock; Nancy E Gruchala; Nadia Fike; Ricardo A Samson; Scott E Klewer; Brent J Barber
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Congenital heart disease     Volume:  3     ISSN:  1747-0803     ISO Abbreviation:  -     Publication Date:    2008 Nov-Dec
Date Detail:
Created Date:  2008-11-28     Completed Date:  2009-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101256510     Medline TA:  Congenit Heart Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  440-2     Citation Subset:  IM    
Affiliation:
University of Arizona College of Medicine, Department of Pediatrics, Tucson, AZ, USA. hainstoc@ohsu.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Chromosomes, Human, X
Electrocardiography
Fludrocortisone / therapeutic use
Fluid Therapy
Humans
Klinefelter Syndrome / complications*,  genetics,  therapy
Male
Postural Orthostatic Tachycardia Syndrome / etiology*,  genetics,  therapy
Sex Factors
Chemical
Reg. No./Substance:
127-31-1/Fludrocortisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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