Document Detail

Postural fall in blood pressure in the elderly in relation to drug treatment and other lifestyle factors.
MedLine Citation:
PMID:  1484937     Owner:  NLM     Status:  MEDLINE    
In a study of 843 independent-living men and women aged between 60 and 87 in Perth, Western Australia, stepwise multiple regression, after correction for initial levels of systolic blood pressure, showed that postural fall in systolic blood pressure was positively related to alcohol intake of more than 20 ml/day, the use of sleeping tablets and higher levels of anxiety on the Spielberger state-trait scale, and negatively related to body mass index. Postural fall in blood pressure was not significantly related to treatment for hypertension, age, sex, patterns of usual physical activity, tea or coffee drinking, or the diagnosis of diabetes mellitus. This analysis is the first to examine the relationship between lifestyle factors and the magnitude of the fall in systolic blood pressure on standing after adjustment for the association between the change in a variable and its initial level. Our analysis suggests the need for further study of the possible role of lifestyle factors such as the use of sleeping tablets and alcohol in postural hypotension in the elderly.
V Burke; L J Beilin; R German; S Grosskopf; J Ritchie; I B Puddey; P Rogers
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Quarterly journal of medicine     Volume:  84     ISSN:  0033-5622     ISO Abbreviation:  Q. J. Med.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1993-02-17     Completed Date:  1993-02-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401027     Medline TA:  Q J Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  583-91     Citation Subset:  IM; S    
University Department of Medicine, Royal Perth Hospital, Western Australia.
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MeSH Terms
Aged, 80 and over
Alcohol Drinking / adverse effects*
Anxiety / complications
Body Mass Index
Central Nervous System Agents / adverse effects*
Hypotension, Orthostatic / etiology*
Middle Aged
Regression Analysis
Smoking / adverse effects
Reg. No./Substance:
0/Central Nervous System Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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