| Postural asymmetry in rats induced by stress and pain stimuli. | |
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MedLine Citation:
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PMID: 7070232 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A significant number of rats (31-68%) subjected to pain stimulation (intraperitoneal injection of 1% or 5% acetic acid, 5 ml/kg), immobilization stress (6 hrs in a supine position) or cold stress (3 hrs at 4-6 degrees C) exhibited postural asymmetry of hind limbs after spinal cord transection at T7 level. The number of rats with right and left limb flexions was approximately equal. Naloxone (2 mg/kg intraperitoneally) prevented the development of postural asymmetry induced by pain and stress stimuli. Postural asymmetry of hind limbs appears to be due to an asymmetric CNS response to stress and pain stimuli. Our data imply that endogenous opioid peptides and opiate receptors may be involved in the regulation of this response. |
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Authors:
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Bakalkin GYa; O G Krivosheev; G K Stolyarov |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Life sciences Volume: 30 ISSN: 0024-3205 ISO Abbreviation: Life Sci. Publication Date: 1982 Mar |
Date Detail:
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Created Date: 1982-06-14 Completed Date: 1982-06-14 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0375521 Medline TA: Life Sci Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 779-83 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetic Acid Acetic Acids / administration & dosage Animals Cold Temperature Injections, Intraperitoneal Male Naloxone / pharmacology Pain / physiopathology* Posture* Rats Restraint, Physical Stress, Physiological / physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Acetic Acids; 465-65-6/Naloxone; 64-19-7/Acetic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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