| Posttransfusion hepatitis A in a neonatal intensive care unit. | |
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MedLine Citation:
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PMID: 6492349 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A single unit of infected blood transfused into 11 neonates resulted in a large multistate outbreak of 55 cases of hepatitis A, 35 of which were symptomatic. The person who donated the blood to the 11 neonates became ill with hepatitis A one week after the donation. Hepatitis A infection was then acquired by nurses and physicians having direct contact with the neonates and by parents and relatives. Three additional newborns who had not received transfusions with the infected unit also acquired hepatitis A. The neonates with hepatitis A were all asymptomatic. The attack rate in susceptible nurses was 16%; in susceptible physicians, 4%. A survey of the relatives of the 11 newborns who received transfusions revealed eight symptomatic cases of hepatitis A in 32 immediate family contacts, ie, mother, father, and siblings, with a resulting attack rate of 25% uncorrected for prior immunity. The setting of the neonatal intensive care unit appears to be ideal for the transmission of hepatitis A. |
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Authors:
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R C Noble; M A Kane; S A Reeves; I Roeckel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: JAMA : the journal of the American Medical Association Volume: 252 ISSN: 0098-7484 ISO Abbreviation: JAMA Publication Date: 1984 Nov |
Date Detail:
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Created Date: 1984-12-12 Completed Date: 1984-12-12 Revised Date: 2006-11-07 |
Medline Journal Info:
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Nlm Unique ID: 7501160 Medline TA: JAMA Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2711-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Transfusion / adverse effects* Cross Infection / epidemiology, transmission* Disease Outbreaks* Epidemiologic Methods Hepatitis A / epidemiology, transmission* Hepatitis A Antibodies Hepatitis Antibodies / analysis Hospital Bed Capacity, 300 to 499 Humans Infant, Newborn Intensive Care Units, Neonatal* Kentucky Medical Records Occupational Diseases / epidemiology, transmission Personnel, Hospital |
| Chemical | |
Reg. No./Substance:
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0/Hepatitis A Antibodies; 0/Hepatitis Antibodies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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