| Postsurgery activation of dormant liver micrometastasis: a case report and review of literature. | |
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MedLine Citation:
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PMID: 20602181 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: We present the case of a 55-year-old woman who underwent a Whipple procedure for pancreatic adenocarcinoma. The preoperative work-up showed no signs of liver metastasis and confirmed the patient's operability, but at less than 40 days postoperatively there were diffuse liver metastasis present on CT. This rapid evolution raises the question whether current staging systems are adequate in determining a patient's operability. It also suggests an interaction between the primary tumor and the host and the existence of disseminated tumor cells. DISCUSSION: In this article, we give an explanation for the clinical evolution presented in our case using the "integrated organ" and the "concomitant resistance" hypotheses. We believe that, if these theories continue to prove their viability, the search for disseminated tumor cells will be essential for good clinical practice in this type of pathology. |
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Authors:
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Bert Deylgat; Frank Van Rooy; Franky Vansteenkiste; Dirk Devriendt; Christophe George |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of gastrointestinal cancer Volume: 42 ISSN: 1941-6636 ISO Abbreviation: J Gastrointest Cancer Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-17 Completed Date: 2011-06-14 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 101479627 Medline TA: J Gastrointest Cancer Country: United States |
Other Details:
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Languages: eng Pagination: 1-4 Citation Subset: IM |
Affiliation:
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Department of General and Digestive Surgery, AZ Groeninge, Kortrijk, Belgium. bert.deylgat@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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secondary*,
surgery* Female Humans Liver Neoplasms / secondary* Middle Aged Pancreatic Neoplasms / pathology, surgery* Postoperative Complications* Tomography, X-Ray Computed Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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