Document Detail

Poststreptococcal reactive arthritis: what is it and how do we know?
MedLine Citation:
PMID:  15150434     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To find out whether poststreptococcal reactive arthritis (PSRA) is a discrete, homogeneous clinical syndrome. METHOD: Literature review from case reports and case series. RESULTS: One hundred and eighty-eight cases were identified. The age distribution was bimodal, with one peak in childhood and one peak in adulthood. Eighty-three percent of streptococcal isolates were group A. The clinical presentation was heterogeneous but appeared different both from that of acute rheumatic fever (ARF) and from that of HLA B27-associated reactive arthritis. Carditis was rare. CONCLUSIONS: The term PSRA encompasses significant heterogeneity. The link between the arthritis and the streptococcal infection is unproven.
S L Mackie; A Keat
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Publication Detail:
Type:  Journal Article; Review     Date:  2004-05-18
Journal Detail:
Title:  Rheumatology (Oxford, England)     Volume:  43     ISSN:  1462-0324     ISO Abbreviation:  Rheumatology (Oxford)     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-19     Completed Date:  2004-08-30     Revised Date:  2007-09-06    
Medline Journal Info:
Nlm Unique ID:  100883501     Medline TA:  Rheumatology (Oxford)     Country:  England    
Other Details:
Languages:  eng     Pagination:  949-54     Citation Subset:  AIM; IM    
Department of Rheumatology, Northwick Park Hospital, Harrow, Middlesex, UK.
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MeSH Terms
Age Distribution
Anti-Infective Agents / therapeutic use
Arthritis, Reactive / complications,  drug therapy,  microbiology*
Child, Preschool
HLA Antigens / analysis
Middle Aged
Streptococcal Infections / complications,  drug therapy,  microbiology*
Streptococcus pyogenes / isolation & purification
Reg. No./Substance:
0/Anti-Infective Agents; 0/HLA Antigens
Comment In:
Rheumatology (Oxford). 2005 Jan;44(1):136; author reply 136-7   [PMID:  15611313 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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