Document Detail


Postresuscitation myocardial dysfunction.
MedLine Citation:
PMID:  11845547     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Postresuscitation myocardial dysfunction is common after prolonged cardiac arrest and can have life-threatening consequences. Experimental data suggest that systolic and diastolic left ventricular function can be adversely effected following successful resuscitation. Such dysfunction can resolve and represents true global myocardial stunning. Identified factors contributing to postresuscitation myocardial dysfunction include prolonged CPR, use of vasoconstricting drugs, and high-energy defibrillation. Potential treatments include dobutamine, KATP channel activators, and 21-aminosteroids. In the author's efforts to improve long-term survival from cardiac arrest, more attention is needed to the postresuscitation period.
Authors:
Karl B Kern
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology clinics     Volume:  20     ISSN:  0733-8651     ISO Abbreviation:  Cardiol Clin     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-15     Completed Date:  2002-07-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8300331     Medline TA:  Cardiol Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-101     Citation Subset:  IM    
Affiliation:
Department of Medicine, Sarver Heart Center, University of Arizona College of Medicine, University Medical Center, Tucson, Arizona, USA. kernk@u.arizona.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Cardiomyopathies / etiology*,  mortality
Cardiopulmonary Resuscitation / adverse effects*,  methods
Clinical Trials as Topic
Disease Models, Animal
Dogs
Heart Arrest / therapy*
Humans
Myocardial Contraction / physiology
Prognosis
Risk Assessment
Risk Factors
Shock, Cardiogenic / etiology,  physiopathology
Survival Rate
Time Factors
Ventricular Dysfunction, Left / etiology*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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