Document Detail

Postprandial glycaemic and insulinaemic responses to GM-resistant starch-enriched rice and the production of fermentation-related H2 in healthy Chinese adults.
MedLine Citation:
PMID:  19930763     Owner:  NLM     Status:  MEDLINE    
Consumption of resistant starch (RS)-enriched foods is associated with decrease in the postprandial glycaemic and insulinaemic responses, accompanied by the production of fermentation-related gases in the large bowel. The present study aimed to determine the postprandial glycaemic and insulinaemic responses to the GM RS-enriched rice and the fermentation-related production of H2 in young and healthy Chinese adults. A total of sixteen young adults (nine men and seven women) were recruited and divided into three groups. Their postprandial glycaemic and insulinaemic responses to 40 g glucose, carbohydrates of RS or wild-type (WT) rice were tested by a crossover model with a washout period of 7 d. The concentrations of blood glucose and insulin as well as breath H2 were measured before and after food intake. Although the mean concentrations of fasting blood glucose, insulin and breath H2 were similar, consumption of the RS rice significantly decreased the values of glycaemic index (GI) and insulin index (II), as compared with the intake of WT rice (48.4 (sem 21.8) v. 77.4 (sem 34.9) for GI, 34.2 (sem 18.9) v. 54.4 (sem 22.4) for II, P < 0.05), respectively. Conversely, intake of the RS rice meal significantly elevated the concentrations of breath H2, as compared with WT rice (38.9 (sem 17.6) v. 10.5 (sem 3.7) parts per million for peak levels of breath H2, P < 0.05) through a period of 16-h tests. Consumption of the GM RS-enriched rice meal decreased the postprandial glycaemic and insulinaemic responses and promoted RS fermentation-related production of H2 in the large bowel of young and healthy Chinese adults.
Min Li; Jian-Hua Piao; Yuan Tian; Wei-Dong Li; Ke-Ji Li; Xiao-Guang Yang
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-11-24
Journal Detail:
Title:  The British journal of nutrition     Volume:  103     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-08     Completed Date:  2010-04-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  1029-34     Citation Subset:  IM    
Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, 29 Nan Wei Road, Xuanwu District, Beijing 100050, People's Republic of China.
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MeSH Terms
Blood Glucose / metabolism*
Breath Tests
Colon / metabolism
Cross-Over Studies
Dietary Carbohydrates / administration & dosage,  metabolism*
Food, Fortified
Food, Genetically Modified*
Glycemic Index / drug effects
Hydrogen / analysis,  metabolism*
Insulin / blood*
Oryza sativa* / chemistry,  genetics
Postprandial Period
Reference Values
Starch / administration & dosage,  metabolism,  pharmacology*
Young Adult
Reg. No./Substance:
0/Blood Glucose; 0/Dietary Carbohydrates; 11061-68-0/Insulin; 1333-74-0/Hydrogen; 9005-25-8/Starch

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