Document Detail

Postprandial gastro-oesophageal reflux in healthy people.
MedLine Citation:
PMID:  23983     Owner:  NLM     Status:  MEDLINE    
Distal oesophageal pH was monitored for three hours after a standard meal in 10 young healthy subjects without symptoms of gastro-oesophageal reflux. Episodes of reflux occurred in nine of these subjects; and, in five, oesophageal pH was less than 5 for between 11 and 75% of the first postprandial hour. Intermittent incompetence of the lower oesophageal sphincter after food must, therefore, be regarded as a normal phenomenon. The method described would be suitable for the evaluation of agents believed to weaken or to strengthen the lower oesophageal sphincter.
M D Kaye
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Gut     Volume:  18     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1977 Sep 
Date Detail:
Created Date:  1978-04-17     Completed Date:  1978-04-17     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  709-12     Citation Subset:  AIM; IM    
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MeSH Terms
Esophagogastric Junction / physiology*
Gastroesophageal Reflux*
Hydrogen-Ion Concentration

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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